Article

Intercellular mRNA trafficking via membrane nanotubes in mammalian cells

2017-05-14

Abstract excerpt

RNAs have been shown to undergo transfer between mammalian cells, though the mechanism behind this phenomenon and its overall importance to cell physiology is not well understood. Numerous publications have suggested that RNAs (microRNAs and incomplete mRNAs) undergo transfer via extracellular vesicles ( e.g . exosomes). However, in contrast to a diffusion-based transfer mechanism, we find that full-length mRNAs...

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Literature Corpus work: e81dae51-2309-5b74-ac4f-718e803637e3
DOI: 10.1101/137836

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