Article

Global analysis of human-to-mouse contact-dependent intercellular mRNA and lncRNA transfer in cell culture

2021-11-28

Abstract excerpt

<h4>Summary</h4> Full-length mRNAs can transfer between adjacent mammalian cells via direct cell-to-cell connections called tunneling nanotubes (TNTs). However, the extent of mRNA transfer at the transcriptome-wide level (the transferome ) is unknown. Here, we analyzed whole transcriptome mRNA and lncRNA transfer between heterogeneous human-mouse cell populations in in vitro co-culture using RNA-sequencing. Our...

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Literature Corpus work: bdd4b569-004f-55f5-8a81-d3c0f372f928
DOI: 10.1101/2021.11.28.470233

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