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Effect of 5-HT<char aid="99740019" id="sub">1A</char> Receptor Gene Polymorphism on Negative and Depressive Symptom Response to Antipsychotic Treatment of Drug-Naive Psychotic Patients

2006-09-29

Abstract excerpt

Objective: The serotonin 5-HT 1A receptor may modulate some of the negative, cognitive, and affective symptoms of schizophrenia and is a potential target of action of some antipsychotic drugs. A functional polymorphism in the promoter region of the 5-HT 1A receptor gene is associated with depression and suicidal behavior. The authors sought to determine whether this polymorphism influences symptom response to anti...

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Identifiers and source

Literature Corpus work
af85d09b-ff2c-52a3-897c-3ea8973b3b24
DOI
10.1176/appi.ajp.163.10.1826
Open publication

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Effect of 5-HT<char aid="99740019" id="sub">1A</char> Receptor Gene Polymorphism on Negative and Depressive Symptom Response to Antipsychotic Treatment of Drug-Naive Psychotic PatientsDOI 10.1176/appi.ajp.163.10.1826
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