Article
Serotonin-1A receptor gene polymorphism and the ability of antipsychotic drugs to improve attention in schizophrenia.
Advances in therapy - 1 May 2010
Sumiyoshi Tomiki, Tsunoda Masahiko, Higuchi Yuko, Itoh Toru, Seo Tomonori, Itoh Hiroko, Suzuki Michio, Kurachi Masayoshi
Abstract excerpt
INTRODUCTION: The purpose of this study was to determine if the functional single nucleotide polymorphisms of rs6259 C(-1019)G in the promoter region, which regulates serotonin 5-HT(1A) receptor transcription, affects the ability of antipsychotic drugs to improve attention in patients with schizophrenia. METHODS: Subjects were neuroleptic-free and meeting DSM-IV-TR criteria for schizophrenia. Psychopathology and...
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