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Article

Polymorphisms of the 5-HT2A receptor gene and clinical response to olanzapine in paranoid schizophrenia.

Neuropsychobiology - 1 Jan 2011

Olajossy-Hilkesberger Luiza, Godlewska Beata, Schosser-Haupt Alexandra, Olajossy Marcin, Wojcierowski Jacek, Landowski Jerzy, Marmurowska-Michałowska Halina, Kasper Siegfried

Abstract excerpt

BACKGROUND: 5-HT2A receptor is strongly implicated in the mode of action of atypical antipsychotic drugs. The aim of the study was to investigate whether the 5-HT2A receptor gene's polymorphisms (His452Tyr and T102C) have an influence on the response to olanzapine in patients with schizophrenia. METHODS: We studied 99 Caucasian schizophrenia patients treated with olanzapine. Psychopathology was measured before...

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Identifiers

PMID: 21912188
DOI: 10.1159/000327602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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