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Article

Effect of 5-HT1A receptor gene polymorphism on negative and depressive symptom response to antipsychotic treatment of drug-naive psychotic patients.

The American journal of psychiatry - 1 Oct 2006

Reynolds Gavin P, Arranz Belen, Templeman Lucy A, Fertuzinhos Sofia, San Luis

Abstract excerpt

OBJECTIVE: The serotonin 5-HT(1A) receptor may modulate some of the negative, cognitive, and affective symptoms of schizophrenia and is a potential target of action of some antipsychotic drugs. A functional polymorphism in the promoter region of the 5-HT(1A) receptor gene is associated with depression and suicidal behavior. The authors sought to determine whether this polymorphism influences symptom response to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Serotonin, 5-HT1A

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Source

Identifiers

PMID: 17012696
DOI: 10.1176/ajp.2006.163.10.1826

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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