Article

Extracellular Vesicle-Associated Syndecan-1 Differentiates Pediatric Brain Tumor Patients with High-Grade from Low-Grade Pilocytic Astrocytoma

2026-01-27

Abstract excerpt

Reliable non-invasive biomarkers for tumor grading and disease monitoring in pediatric brain tumors are an unmet clinical need. Circulating extracellular vesicles (EVs) carrying molecular cargo reflective of tumor biology, offer promise as liquid biopsy tools. We have previously discovered EV-associated Syndecan-1 (SDC1) to be overexpressed in malignant brain tumors, but its value as a biomarker in pediatric disea...

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Literature Corpus work: af407a57-5ad5-5827-a5ea-f0b8d9d73f06
DOI: 10.64898/2026.01.22.26344286

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