Article

Platelet transcriptomic signatures in pediatric brain tumors distinguish cancer from cancer-free control

2025-12-17

Abstract excerpt

<h4>Background:</h4> Malignant pediatric brain tumors remain the leading cause of cancer-related mortality in children. Current diagnostics rely on imaging and invasive biopsy, which may not capture tumor heterogeneity. Liquid biopsy-based biomarkers such as tumor-educated platelets have shown diagnostic value in adult cancers, but their utility in pediatric brain tumors has not been investigated. <h4>Methods:</h...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f05ca658-4de8-5ea4-960c-b6a96c9ef792
DOI: 10.64898/2025.12.17.25341356

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Platelet transcriptomic signatures in pediatric brain tumors distinguish cancer from cancer-free controlDOI 10.64898/2025.12.17.25341356Read

Pediatric High Grade Glioma Resources From the Children’s Brain Tumor Tissue Consortium (CBTTC) and Pediatric Brain Tumor Atlas (PBTA)Semantic proximity Read

A living pediatric brain tumor atlas reveals histomolecular diversity and therapeutic vulnerabilities for precision neuro-oncologySemantic proximity Read

Tumor and immune cell types interact to produce heterogeneous phenotypes of pediatric high-grade glioma.Semantic proximity Read

Identifying tumor type and cell type-specific gene expression alterations in pediatric central nervous system tumorsSemantic proximity Read

Tumor type and cell type-specific gene expression alterations in diverse pediatric central nervous system tumors identified using single nuclei RNA-seqSemantic proximity Read

Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With CancerSemantic proximity Read

Circulating tumor DNA precision oncology enables effective and sensitive molecular diagnostics and actionable target detection in pediatric solid tumors - the INFORM experienceSemantic proximity Read

A longitudinal single-cell and spatial multiomic atlas of pediatric high-grade gliomaSemantic proximity Read

The Use of Circulating Tumor DNA Assays and Liquid Biopsies in Pediatric Brain Tumors: A ReviewSemantic proximity Read

Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer.Semantic proximity Read

Genomic Analysis of Childhood Brain Tumors: Methods for Genome-Wide Discovery and Precision Medicine Become MainstreamSemantic proximity Read

The Emerging Molecular Foundations of Pediatric Brain TumorsSemantic proximity Read