Article

Pharmacogenetics at scale: An analysis of the UK Biobank

2020-06-02

Abstract excerpt

Pharmacogenetics (PGx) studies the influence of genetic variation on drug response. Clinically actionable associations inform guidelines created by the Clinical Pharmacogenetics Implementation Consortium (CPIC), but the broad impact of genetic variation on entire populations is not well-understood. We analyzed PGx allele and phenotype frequencies for 487,409 participants in the U.K. Biobank, the largest PGx study...

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Literature Corpus work: af400bb4-2bc7-5656-b171-d371aec89045
DOI: 10.1101/2020.05.30.125583

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