Frequencies of pharmacogenomic alleles across biogeographic groups in a large-scale biobank.

doi:10.1016/j.ajhg.2023.09.001

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Frequencies of pharmacogenomic alleles across biogeographic groups in a large-scale biobank.

American journal of human genetics - 5 Oct 2023

Li Binglan, Sangkuhl Katrin, Whaley Ryan, Woon Mark, Keat Karl, Whirl-Carrillo Michelle, Ritchie Marylyn D, Klein Teri E

Abstract excerpt

Pharmacogenomics (PGx) is an integral part of precision medicine and contributes to the maximization of drug efficacy and reduction of adverse drug event risk. Accurate information on PGx allele frequencies improves the implementation of PGx. Nonetheless, curating such information from published allele data is time and resource intensive. The limited number of allelic variants in most studies leads to an...

Topics

Humans
Pharmacogenetics
Alleles
Biological Specimen Banks
Precision Medicine
Gene Frequency
Liver-Specific Organic Anion Transporter 1

Source

Open in PubMed Open full text

Identifiers

PMID: 37757824
DOI: 10.1016/j.ajhg.2023.09.001
PMCID: PMC10577080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics