Article
Drug Response Pharmacogenetics for 200,000 UK Biobank Participants.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2021
McInnes Gregory, Altman Russ B
Abstract excerpt
Pharmacogenetics studies how genetic variation leads to variability in drug response. Guidelines for selecting the right drug and right dose for patients based on their genetics are clinically effective, but are widely unused. For some drugs, the normal clinical decision making process may lead to the optimal dose of a drug that minimizes side effects and maximizes effectiveness. Without measurements of genotype,...
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