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Article

The global spectrum of protein-coding pharmacogenomic diversity.

The pharmacogenomics journal - 1 Jan 2018

Wright G E B, Carleton B, Hayden M R, Ross C J D

Abstract excerpt

Differences in response to medications have a strong genetic component. By leveraging publically available data, the spectrum of such genomic variation can be investigated extensively. Pharmacogenomic variation was extracted from the 1000 Genomes Project Phase 3 data (2504 individuals, 26 global populations). A total of 12 084 genetic variants were found in 120 pharmacogenes, with the majority (90.0%) classified...

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PMID: 27779249
DOI: 10.1038/tpj.2016.77
PMCID: PMC5817389

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