Article

Circulating immune cell phenotype dynamics reflect the strength of tumor-immune cell interactions in patients during immunotherapy

2020-03-26

Abstract excerpt

The extent that immune cell phenotypes in the peripheral blood reflect within-tumor immune activity prior to and early in cancer therapy is unclear. To address this question, we studied the population dynamics of tumor and immune cells, and immune phenotypic changes, using clinical tumor and immune cell measurements and single cell genomic analyses. These samples were serially obtained from a cohort of advanced ga...

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Literature Corpus work: af3a4369-2b8a-5c17-b046-139698a94642
DOI: 10.1101/2020.03.24.993923

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