Article

From tumor microenvironment to immuno-therapeutic outcomes for solid tumors: A systems theoretic approach

2024-09-27

Abstract excerpt

Increasing evidence suggests the tumor microenvironment (TME) governs solid tumor response to immune checkpoint inhibition (ICI). Decoding the relationship between the cell compositional diversity of the tumor microenvironment (TME) and the therapeutic outcomes has been a longstanding problem in solid tumor research. In this work, we develop a systems-theoretic formalism to decipher the key mechanisms of growth, p...

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Identifiers and source

Literature Corpus work: 5935dff0-675a-5289-bd1a-38ec52b7926f
DOI: 10.1101/2024.09.26.615155

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