Article
Current concepts in the epigenetic regulation of cardiac fibrosis.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000
Fatehi Hassanabad Ali, Zarzycki Anna N, Patel Vaibhav B, Fedak Paul W M
Abstract excerpt
Cardiac fibrosis is a significant driver of congestive heart failure, a syndrome that continues to affect a growing patient population globally. Cardiac fibrosis results from a constellation of complex processes at the transcription, receptor, and signaling axes levels. Various mediators and signaling cascades, such as the transformation growth factor-beta pathway, have been implicated in the pathophysiology of...
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