Causal association between sepsis and acute respiratory distress syndrome: Evidence from a 2-sample Mendelian randomization study.

Abstract excerpt

Acute respiratory distress syndrome (ARDS) is a life-threatening respiratory failure syndrome, and sepsis is a dysregulated host response to infection. Although sepsis is a major ARDS trigger, the causal relationship at the genetic level remains unestablished. This study assesses the causal effect of sepsis on the risk of ARDS using 2-sample Mendelian randomization (MR). We performed a 2-sample MR analysis using...

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