Article
Genome-wide association study of paediatric bacteraemia and sepsis.
EBioMedicine - 1 Jul 2026
Lawless Dylan, Hodel Flavia Aurelia, Thorball Christian W, Xu Zhi Ming, Borghesi Alessandro, Giannoni Eric, Trück Johannes, Stocker Martin, Posfay-Barbe Klara M, Heininger Ulrich, Bernhard-Stirnemann Sara, Niederer-Loher Anita, Kahlert Christian R, Natalucci Giancarlo, Relly Christa, Berger Christoph, Riedel Thomas, Aebi Christoph, Agyeman Philipp, Fellay Jacques, Schlapbach Luregn J
Abstract excerpt
BACKGROUND: Sepsis is defined as a dysregulated host response to infection leading to organ dysfunction. It represents a major global health concern, particularly in childhood. The underlying pathophysiological and genetic mechanisms remain insufficiently understood. METHODS: Using samples and clinical data from 650 children enrolled in the Swiss Pediatric Sepsis Study, a national multicentre cohort for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.