Article

Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range

2021-12-28

Abstract excerpt

<h4>ABSTRACT</h4> Investigation of potential hosts of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is crucial to understanding future risks of spillover and spillback. SARS-CoV-2 has been reported to be transmitted from humans to various animals after requiring relatively few mutations.[1] There is significant interest in describing how the virus interacts with mice as they are well adapted to...

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Literature Corpus work: aef69a1d-2254-5388-9a7c-bad722f5a42f
DOI: 10.1101/2021.12.27.474250

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