Article

The Endosomal pH Regulator NHE6 is Required for Insulin-Stimulated Glucose Uptake in Adipocytes

2023-07-30

Abstract excerpt

<h4>Objective</h4> Trafficking of GLU cose T ransporter isoform 4 (GLUT4) from the adipocyte vesicular pool to the cell surface is tightly regulated by insulin to maintain glucose homeostasis in response to changing demands in energy consumption. Previously, endosomal Na + /H + exchanger 6 (NHE6, gene name SLC9A6 ) was identified in adipocyte plasma membranes and shown to associate with GLUT4-positive vesic...

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Literature Corpus work: aecc048e-b1d3-5cc8-9b2f-3083b70b5693
DOI: 10.1101/2023.07.30.551163

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