Article
Syntaxin 16 controls the intracellular sequestration of GLUT4 in 3T3-L1 adipocytes.
Biochemical and biophysical research communications - 25 Aug 2006
Proctor Kirsty M, Miller Steven C M, Bryant Nia J, Gould Gwyn W
Abstract excerpt
The regulated delivery of Glut4-containing vesicles to the plasma membrane is a specialised example of regulated membrane trafficking. Present models favour the transporter trafficking through two inter-related endosomal cycles. The first is the proto-typical endosomal system. This is a fast trafficking event that, in the absence of insulin, serves to internalise Glut4 from the plasma membrane. Once in this...
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