Article

Network Analyses of Brain Tumor Patients’ Multiomic Data Reveals Pharmacological Opportunities to Alter Cell State Transitions

2024-05-21

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma Multiforme (GBM) remains a particularly difficult cancer to treat, and survival outcomes remain poor. In addition to the lack of dedicated drug discovery programs for GBM, extensive intratumor heterogeneity and epigenetic plasticity related to cell-state transitions are major roadblocks to successful drug therapy in GBM. To study these phenomenon, publicly available snRNAse...

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Literature Corpus work: ae5ae893-484b-5977-a60d-35aefb7cfa93
DOI: 10.21203/rs.3.rs-4391296/v1

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