Article

Identifying Prognostic Cell State Interactions in the Tumor Microenvironment of IDH-Mutant Gliomas Using CSI-TME

2024-11-03

Abstract excerpt

Intercellular communication between distinct transcriptional states of various cell types in the tumor microenvironment (TME) influence the progression and clinical outcome of the tumors. Details of such clinically relevant cellular state interactions (CSIs) in IDH-mutant gliomas remain obscure. Here we developed CSI-TME, a computational pipeline that deconvolves cell type-specific gene expression from bulk transc...

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Literature Corpus work: 6ca3a646-9adc-5e02-bb12-686c4ef0fbd5
DOI: 10.1101/2024.10.29.620901

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