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α-Mangostin Inhibits LPS-Induced Bone Resorption by Restricting Osteoclastogenesis Via NF-κB and MAPK Signaling

2021-12-13

Abstract excerpt

<h4>Background: </h4> Excessive activation of osteoclasts is an important cause of imbalance in bone remodeling, which further leads to pathological bone destruction. This is a clear feature of many osteolytic diseases, such as rheumatoid arthritis, osteoporosis, and osteolysis around the prosthesis. Based on the fact that many natural compounds have therapeutic potential for treating these diseases by suppressing...

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Literature Corpus work
ae38d767-c017-5831-8e95-2ca4b8e15548
DOI
10.21203/rs.3.rs-1141803/v1
Open publication

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