Article

Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-κb and p38 MAPK Signaling Pathways

2019-12-31

Abstract excerpt

<title>Abstract</title> <p>Backgroud: Aseptic prosthetic loosening is one of main factor producing poor prognosis of limb function after joint replacement and requiring troublesome revision surgery. It is featured by wear particle–induced periprosthetic osteolysis mediated by excessive osteoclasts activated in inflammatory cell context. In our previous study, some natural compounds showing anti-osteoclast trait w...

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Literature Corpus work: 21258d80-d77f-514b-9561-b7c24e2c1004
DOI: 10.21203/rs.2.19812/v1

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Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-κb and p38 MAPK Signaling PathwaysDOI 10.21203/rs.2.19812/v1Read

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