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Marein prevented LPS-induced osteoclastogenesis by regulating the NF-κB pathway in vitro

2022-01-06

Abstract excerpt

Gram-negative bacterial infection causes many bone diseases such as osteolysis, osteomyelitis and septic arthritis. Lipopolysaccharide (LPS), a bacteria product, played an important role in this process. Drugs that inhibited LPS-induced osteoclastogenesis were urgently needed for the prevention of bone destruction in infective bone diseases. Marein, a major bioactive compound of Coreopsis.tinctoria , which possess...

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Literature Corpus work
9a866b37-ea05-547a-98b3-0b8f371630cd
DOI
10.21203/rs.3.rs-112215/v2
Open publication

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