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Cirsilineol inhibits RANKL-induced osteoclast activity and ovariectomy-induced bone loss via NK-κβ/ERK/p38 signaling pathways

2024-01-24

Abstract excerpt

<title>Abstract</title> <p>Background Postmenopausal osteoporosis is a chronic metabolic bone disease caused by excessive osteoclast formation and function. Targeting osteoclast differentiation and activity can modulate bone resorption and alleviate osteoporosis. Cirsilineol, an active constituent of vestita Wall, has shown numerous biological activities and has been used to treat many metabolic diseases. Howeve...

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Literature Corpus work
16720939-2285-50b9-b7a3-7ef0f77ec465
DOI
10.21203/rs.3.rs-3849118/v1
Open publication

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Cirsilineol inhibits RANKL-induced osteoclast activity and ovariectomy-induced bone loss via NK-κβ/ERK/p38 signaling pathwaysDOI 10.21203/rs.3.rs-3849118/v1
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