Article

Functional role of myosin-binding protein H in thick filaments of developing vertebrate fast-twitch skeletal muscle

2024-05-13

Abstract excerpt

Myosin-binding protein H (MyBP-H) is a component of the vertebrate skeletal muscle sarcomere with sequence and domain homology to myosin-binding protein C (MyBP-C). Whereas skeletal muscle isoforms of MyBP-C (fMyBP-C, sMyBP-C) modulate muscle contractility via interactions with actin thin filaments and myosin motors within the muscle sarcomere “C-zone,” MyBP-H has no known function. This is in part due to MyBP-H h...

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Literature Corpus work: adfd2c7d-897a-5403-8826-48815500da7d
DOI: 10.1101/2024.05.10.593199

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