Article

Unlocking the Role of sMyBP-C: A Key Player in Skeletal Muscle Development and Growth

2023-10-25

Abstract excerpt

Skeletal muscle is the largest organ in the body, responsible for gross movement and metabolic regulation. Recently, variants in the MYBPC1 gene have been implicated in a variety of developmental muscle diseases, such as distal arthrogryposis. How MYBPC1 variants cause disease is not well understood. Here, through a collection of novel gene-edited mouse models, we define a critical role for slow myosin binding p...

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Literature Corpus work: feb543c3-e0e3-5d8e-8557-3f277e79c251
DOI: 10.1101/2023.10.23.563591

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