Article
The Caenorhabditis elegans MYOD homologue HLH-1 is essential for proper muscle function and complete morphogenesis.
Development (Cambridge, England) - 1 Jun 1994
Chen L, Krause M, Sepanski M, Fire A
Abstract excerpt
A family of muscle-specific helix-loop-helix transcription factors (myoD, myogenin, myf-5 and MRF4) has been implicated in the control of vertebrate skeletal myogenesis. Searches for homologues of this family in Caenorhabditis elegans identified a single family member, hlh-1, which is expressed i...
Topics
- Alleles
- Animals
- Base Sequence
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- DNA Primers
- Helix-Loop-Helix Motifs
- Helminth Proteins
- Microscopy, Electron
- Molecular Sequence Data
- Morphogenesis
- Muscle Proteins
- Muscles
- Mutagenesis
- MyoD Protein
- Myogenic Regulatory Factors
- Nuclear Proteins
- Phenotype