Article

Investigating the role of nuclear encoded mitochondrial genes in the onset of type 2 diabetes

2021-01-01

Abstract excerpt

Mitochondrial dysfunction has long been implicated in Type 2 diabetes (T2D). This rela- tionship appears to be bidirectional, with evidence that mitochondrial dysfunction is both caused by and causal of T2D-related phenotypes. A potential causal role in T2D onset would be supported by evidence of a genetic predisposition to mitochondrial dysfunction, since inherited genetic risk factors precede and contribute to d...

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Literature Corpus work: ade88663-489d-51d0-8e93-c1384b2918c1
DOI: 10.25560/90969

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