Article

Title: “Mitochondrial GWAS and Association of Nuclear - Mitochondrial Epistasis with BMI in T1DM Patients”

2018-10-05

Abstract excerpt

Mitochondria are organelles whose main role is energy production and might influence obesity. They are the only organelles with their own genome. Here we have genotyped 435 patients with type 1 diabetes using Illumina Infinium Omni Express Exome-8 v1.4 arrays and performed mitoGWAS on BMI. We have analyzed additive interactions between mitochondrial and nuclear variants in genes known to be associated with mitocho...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 44ea4f9f-dc71-5b61-a5d9-ad82e9c6c7d4
DOI: 10.1101/436519

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Title: “Mitochondrial GWAS and Association of Nuclear - Mitochondrial Epistasis with BMI in T1DM Patients”DOI 10.1101/436519Read

Mitochondrial GWAS and association of nuclear – mitochondrial epistasis with BMI in T1DM patientsSemantic proximity Read

Mitochondrial genetic variants identified to be associated with BMI in adults.Semantic proximity Read

Mitochondrial dysfunction and onset of type 2 diabetes along with its complications: a multi-omics Mendelian randomization and colocalization study.Semantic proximity Read

Mitochondrial alteration in type 2 diabetes and obesity: An epigenetic linkSemantic proximity Read

Identification of novel type 2 diabetes candidate genes involved in the crosstalk between the mitochondrial and the insulin signaling systems.Semantic proximity Read

Integrative analysis of Mendelian randomization and Bayesian colocalization highlights four genes with putative BMI-mediated causal pathways to diabetes.Semantic proximity Read

Mitochondrial Epigenetic Changes Link to Increased Diabetes Risk and Early‐Stage Prediabetes IndicatorSemantic proximity Read

Investigating the role of nuclear encoded mitochondrial genes in the onset of type 2 diabetesSemantic proximity Read

Changes in Mitochondrial Epigenome in Type 2 Diabetes MellitusSemantic proximity Read

Identification of three genetic variants as novel susceptibility loci for body mass index in a Japanese population.Semantic proximity Read

ASSOCIATION ANALYSIS OF MITOCHONDRIAL HETEROPLASMIC VARIANTS AND CARDIOMETABOLIC TRAITSSemantic proximity Read

Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study.Semantic proximity Read