Article

Removing unwanted variation in a differential methylation analysis of Illumina HumanMethylation450 array data

2015-05-07

Abstract excerpt

<h4>ABSTRACT</h4> Due to their relatively low-cost per sample and broad, gene-centric coverage of CpGs across the human genome, Illumina’s 450k arrays are widely used in large scale differential methylation studies. However, by their very nature, large studies are particularly susceptible to the effects of unwanted variation. The effects of unwanted variation have been extensively documented in gene expression ar...

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Literature Corpus work: adce0aed-6b9c-5097-adb3-1a9168efb2a2
DOI: 10.1101/019042

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