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Article

A comprehensive overview of Infinium HumanMethylation450 data processing.

Briefings in bioinformatics - 1 Nov 2014

Dedeurwaerder Sarah, Defrance Matthieu, Bizet Martin, Calonne Emilie, Bontempi Gianluca, Fuks François

Abstract excerpt

Infinium HumanMethylation450 beadarray is a popular technology to explore DNA methylomes in health and disease, and there is a current explosion in the use of this technique. Despite experience acquired from gene expression microarrays, analyzing Infinium Methylation arrays appeared more complex than initially thought and several difficulties have been encountered, as those arrays display specific features that...

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Identifiers

PMID: 23990268
DOI: 10.1093/bib/bbt054
PMCID: PMC4239800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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