Article
A data-driven approach to preprocessing Illumina 450K methylation array data.
BMC genomics - 1 May 2013
Pidsley Ruth, Y Wong Chloe C, Volta Manuela, Lunnon Katie, Mill Jonathan, Schalkwyk Leonard C
Abstract excerpt
BACKGROUND: As the most stable and experimentally accessible epigenetic mark, DNA methylation is of great interest to the research community. The landscape of DNA methylation across tissues, through development and in disease pathogenesis is not yet well characterized. Thus there is a need for rapid and cost effective methods for assessing genome-wide levels of DNA methylation. The Illumina Infinium...
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