Article
Preprocessing, normalization and integration of the Illumina HumanMethylationEPIC array
2016-07-23
Abstract excerpt
The minfi package is widely used for analyzing Illumina DNA methylation array data. Here we describe modifications to the minfi package required to support the HumanMethylationEPIC (”EPIC”) array from Illumina. We discuss methods for the joint analysis and normalization of data from the HumanMethylation450 (”450k”) and EPIC platforms. We also introduce the single-sample Noob ( ssNoob ) method, a normalization p...
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Identifiers and source
- Literature Corpus work
- 9d8c262f-ecbe-52e3-83d8-c8a559a22948
- DOI
- 10.1101/065490