Article
Identifying mislabeled and contaminated DNA methylation microarray data: an extended quality control toolset with examples from GEO.
Clinical epigenetics - 1 Jan 2018
Heiss Jonathan A, Just Allan C
Abstract excerpt
Background: Mislabeled, contaminated or poorly performing samples can threaten power in methylation microarray analyses or even result in spurious associations. We describe a set of quality checks for the popular Illumina 450K and EPIC microarrays to identify problematic samples and demonstrate their application in publicly available datasets. Methods: Quality checks implemented here include 17 control metrics...
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