Article

Mendelian Randomization Identifies Circulating Proteins APOM and TNXB as Biomarkers for Steroid Sensitive Nephrotic Syndrome

2025-10-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Steroid-sensitive nephrotic syndrome (SSNS) is the most common glomerular disease in children worldwide. Current treatments are not targeted and lead to serious adverse effects. We sought to identify circulating proteins associated with SSNS in European children using an unbiased two-sample Mendelian randomization (MR) and colocalization approach to inform novel drug targe...

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Literature Corpus work: adbc91ea-95e4-5562-a14f-8fd8b2430758
DOI: 10.1101/2025.10.03.25337251

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