Article

Multi-population genome-wide association study implicates both immune and non-immune factors in the etiology of pediatric steroid sensitive nephrotic syndrome

2022-09-14

Abstract excerpt

<h4>ABSTRACT</h4> Pediatric steroid-sensitive nephrotic syndrome (pSSNS) is the most common childhood glomerular disease. Previous genome-wide association studies (GWAS) identified a risk locus in the HLA Class II region and three additional signals. But the genetic architecture of pSSNS, and its genetically driven pathobiology, is largely unknown. We conducted a multi-population GWAS meta-analysis in 38,463 parti...

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Literature Corpus work: 63f216a4-4041-5db4-858c-b89882985496
DOI: 10.1101/2022.09.13.22279644

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