Article

Circulating inflammatory proteins may be potential drug targets for Idiopathic Membranous Nephropathy: proteome-wide Mendelian Randomization and colocalization analysis

2023-12-13

Abstract excerpt

<h4>Background</h4> Idiopathic membranous nephropathy (IMN) is a predominant cause of nephrotic syndrome among adults. Existing drugs are ineffective in about one-third of IMN patients, and the high recurrence rate makes them far from satisfactory. Therefore, it is imperative to find new therapeutic targets for membranous nephropathy. Circulating inflammatory proteins in plasma have been found to be related to the...

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Literature Corpus work: 6012f8f9-99fc-58bf-81b1-a1963f5d18f8
DOI: 10.1101/2023.12.11.23299722

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