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Article

Therapeutic Targets for Diabetic Kidney Disease: Proteome-Wide Mendelian Randomization and Colocalization Analyses.

Diabetes - 1 Apr 2024

Zhang Wei, Ma Leilei, Zhou Qianyi, Gu Tianjiao, Zhang Xiaotian, Xing Haitao

Abstract excerpt

At present, safe and effective treatment drugs are urgently needed for diabetic kidney disease (DKD). Circulating protein biomarkers with causal genetic evidence represent promising drug targets, which provides an opportunity to identify new therapeutic targets. Summary data from two protein quantitative trait loci studies are presented, one involving 4,907 plasma proteins data from 35,559 individuals and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38211557
DOI: 10.2337/db23-0564
PMCID: PMC10958583

Genes

TGFBI

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