Article

Integrative proteomics and transcriptomics of human T-cells reveals temporal metabolic reprogramming following TCR-induced activation

2023-03-20

Abstract excerpt

T-cells are critical components of the adaptive immune system. Upon activation, they acquire effector functions through a complex interplay between mRNA transcripts and proteins, the landscape of which remains to be fully elucidated. In this resource article, we present an integrative temporal proteomic and transcriptomic analysis of primary human CD4 + and CD8 + T-cells following ex vivo activation with anti-C...

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Literature Corpus work: ed0e1237-a6d5-5a1c-be57-e03f20a0663a
DOI: 10.1101/2023.03.17.532022

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