Article
Genetics, Genome-Wide Association Studies, and Menarche.
Seminars in reproductive medicine - 1 Jul 2016
Witchel Selma Feldman
Abstract excerpt
Puberty is characterized by maturation of the hypothalamic-pituitary-gonadal axis, development of secondary sexual features, increased linear growth velocity, maturation of the epiphyses limiting additional growth, and achievement of menarche. The age at menarche appears to have a significant genetic component. With the advent of genome-wide association studies (GWASs), the genome has been interrogated to find...
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