Article

SharpTNI: Counting and Sampling Parsimonious Transmission Networks under a Weak Bottleneck

2019-11-14

Abstract excerpt

<h4>Background</h4> Technological advances in genomic sequencing are facilitating the reconstruction of transmission histories during outbreaks in the fight against infectious diseases. However, accurate disease transmission inference using this data is hindered by a number of challenges due to within-host pathogen diversity and weak transmission bottlenecks, where multiple genetically-distinct pathogenic strains...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ad70d51e-187c-5f6e-b004-e8a8b386cda5
DOI: 10.1101/842237

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SharpTNI: Counting and Sampling Parsimonious Transmission Networks under a Weak BottleneckDOI 10.1101/842237Read

JUNIPER: Reconstructing Transmission Events from Next-Generation Sequencing Data at ScaleSemantic proximity Read

JUNIPER: Reconstructing Transmission Events from Next-Generation Sequencing Data at ScaleSemantic proximity Read

Scalable deep-learning-based inference of time-varying transmission dynamics from outbreak phylogeniesSemantic proximity Read

Integrating Transmission Dynamics and Pathogen Evolution Through a Bayesian ApproachSemantic proximity Read

Inference of infectious disease transmission using multiple genomes per hostSemantic proximity Read

ScTree: Scalable and robust mechanistic integration of epidemiological and genomic data for transmission tree inferenceSemantic proximity Read

Biological causes and impacts of rugged tree landscapes in phylodynamic inferenceSemantic proximity Read

Simultaneous inference of phylogenetic and transmission trees in infectious disease outbreaks.Semantic proximity Read

Phylogenetic-informed graph deep learning to classify dynamic transmission clusters in infectious disease epidemicsSemantic proximity Read

Fundamental identifiability limits in molecular epidemiologySemantic proximity Read

Fundamental Identifiability Limits in Molecular EpidemiologySemantic proximity Read

EpiFusion: Joint inference of the effective reproduction number by integrating phylodynamic and epidemiological modelling with particle filteringSemantic proximity Read