Article

Biological causes and impacts of rugged tree landscapes in phylodynamic inference

2025-06-12

Abstract excerpt

Phylodynamic analysis has been instrumental in elucidating epidemiological and evolutionary dynamics of pathogens. Bayesian phylodynamics integrates out phylogenetic uncertainty, which is typically substantial in phylodynamic datasets due to limited genetic diversity. Phylodynamic inference does not, however, scale with modern datasets, partly due to difficulties in traversing tree space. Here, we characterize tre...

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Literature Corpus work: fb0c46f3-69ae-520b-8f20-ba4ad60302f2
DOI: 10.1101/2025.06.10.657742

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