Article

Autophagy-dependent alternative splicing event produces a more stable ribosomal protein S24 isoform that aids in hypoxic cell survival

2023-09-25

Abstract excerpt

<h4>ABSTRACT</h4> Overlapping or convergent stress-activated molecular pathways exist to coordinate cell fate in response to stimuli such as hypoxia, oxidative stress, DNA damage, and unfolded proteins. Cells can remodel the splicing and translation machineries to mount a specialized gene expression response to certain stresses. Here, we show that hypoxic human cells in 2D and 3D culture models increase the relat...

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Literature Corpus work: ad54ec5b-4b7c-556e-b05d-74302f0edbaa
DOI: 10.1101/2023.09.25.559338

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Autophagy-dependent alternative splicing event produces a more stable ribosomal protein S24 isoform that aids in hypoxic cell survivalDOI 10.1101/2023.09.25.559338Read

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