Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial ribosomal proteins: potential targets for cancer prognosis and therapy

30 Apr 2025

Abstract excerpt

Mitochondrial ribosomal proteins (MRPs) are essential components of mitochondrial ribosomes, responsible for translating proteins encoded by mitochondrial DNA and maintaining mitochondrial energy metabolism and function. Emerging evidence suggests that MRPs exhibit significant expression changes in multiple cancer types, profoundly affecting tumor biology through modulating oxidative stress levels, inducing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Mitochondrial Function and Pathology
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40371222
DOI: 10.3389/fonc.2025.1586137

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial ribosomal proteins: potential targets for cancer prognosis and therapyPMID 40371222Read ↗

Potential of Mitochondrial Ribosomal Genes as Cancer Biomarkers Demonstrated by Bioinformatics ResultsSemantic proximity Read ↗

MRPS28 serves as a biomarker of diagnostic, prognostic, and immune modulation in pan-cancer and promotes breast cancer malignant phenotypes.Semantic proximity Read ↗

The role of the mitochondrial ribosomal protein family in detecting hepatocellular carcinoma and predicting prognosis, immune features, and drug sensitivitySemantic proximity Read ↗

Expression and prognosis analysis of mitochondrial ribosomal protein family in breast cancerSemantic proximity Read ↗

Mitochondrial ribosomal protein L3 (MRPL3): An early diagnostic biomarker and potential molecular target in pancreatic cancerSemantic proximity Read ↗

UBASH3B-mediated MRPL12 Y60 dephosphorylation inhibits LUAD development by driving mitochondrial metabolism reprogrammingSemantic proximity Read ↗

The Interplay Between the MYC Oncogene and Ribosomal Proteins in Osteosarcoma Onset and Progression: Potential Mechanisms and Indication of Candidate Therapeutic TargetsSemantic proximity Read ↗

Pan-cancer analysis of the oncogenic effects of ribosomal protein L13 (MRPL13) and validation in hepatocellular carcinomaSemantic proximity Read ↗

Mitochondrial remodeling in colorectal cancer initiation, progression, metastasis, and therapy: A reviewSemantic proximity Read ↗

Decoding the ribosome's hidden language: rRNA modifications as key players in cancer dynamics and targeted therapiesSemantic proximity Read ↗

A novel biomarker, MRPS12 functions as a potential oncogene in ovarian cancer and is a promising prognostic candidateSemantic proximity Read ↗

Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.