Article

sNucConv: A bulk RNA-seq deconvolution method trained on single-nucleus RNA-seq data to estimate cell-type composition of human subcutaneous and visceral adipose tissues

2023-07-17

Abstract excerpt

Deconvolution algorithms rely on single-cell RNA-sequencing (scRNA-seq) data applied onto bulk RNA-sequencing (bulk RNA-seq) to extract information on the cell-types composition and proportions comprising a certain tissue. Adipose tissues’ cellular composition exhibits enormous plasticity in response to weight changes and high variance at different anatomical locations (depots). However, adipocytes – the functiona...

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Literature Corpus work: 4a4700f6-54f0-5804-a3ed-1d8d61e23ce0
DOI: 10.1101/2023.07.16.549187

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