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Neonatal Microglia and Their Secretome as Mediators of Brain Repair

2025-09-22

Abstract excerpt

Microglia are essential regulators of myelin integrity and repair, yet their regenerative capacity declines with ageing and in neurodegenerative diseases such as multiple sclerosis (MS). Neonatal microglia retain a uniquely reparative program that may offer insight into restoring lost functions in the adult CNS. Here we show that transplantation of neonatal microglia ameliorates disability, reduces leukocyte infil...

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Identifiers and source

Literature Corpus work
acce033d-b741-583a-9d39-b8c96447d930
DOI
10.1101/2025.09.21.676806
Open publication

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Neonatal Microglia and Their Secretome as Mediators of Brain RepairDOI 10.1101/2025.09.21.676806
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