Article
Convergence between Microglia and Peripheral Macrophages Phenotype during Development and Neuroinflammation.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 22 Jan 2020
Grassivaro Francesca, Menon Ramesh, Acquaviva Massimo, Ottoboni Linda, Ruffini Francesca, Bergamaschi Andrea, Muzio Luca, Farina Cinthia, Martino Gianvito
Abstract excerpt
Differently from other myeloid cells, microglia derive exclusively from precursors originating within the yolk sac and migrate to the CNS under development, without any contribution from fetal liver or postnatal hematopoiesis. Consistent with their unique ontology, microglia may express specific physiological markers, which have been partly described in recent years. Here we wondered whether profiles...
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