Article

Homologous recombination deficiency in ovarian high-grade serous carcinoma by self-reported race

2025-01-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Approximately half of ovarian high-grade serous carcinomas (HGSC) have homologous recombination deficiency (HRD). However, HRD is not well-characterized in Black individuals. <h4>Objective</h4> To characterize HGSC HRD by self-reported race and evaluate whether differences in HRD are associated with ovarian cancer mortality. <h4>Study population</h4> Cohort study using data co...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: acc0b5a6-fb94-5106-b0d1-ec0fd3ad1639
DOI: 10.1101/2025.01.21.25320918

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Homologous recombination deficiency in ovarian high-grade serous carcinoma by self-reported raceDOI 10.1101/2025.01.21.25320918Read

Genomic Characterization of High-Grade Serous Ovarian Carcinoma Reveals Distinct Somatic Features in Black Individuals.Semantic proximity Read

Homologous Recombination Deficiency in Ovarian and Breast Cancers: Biomarkers, Diagnosis, and TreatmentSemantic proximity Read

Clinical characteristics of ovarian cancer classified by BRCA1, BRCA2, and RAD51C status.Semantic proximity Read

Pathogenic germline variants among patients with ovarian cancer by self-reported ancestry: A commercial laboratory collaborative research registry study.Semantic proximity Read

Genomic Analyses of Germline and Somatic Variation in High-Grade Serous Ovarian CancerSemantic proximity Read

Prevalence of homologous recombination deficiency in ovarian, primary peritoneal, and/or fallopian tube cancer: results from HALO-Taiwan subset.Semantic proximity Read

[Analysis of homologous recombination deficiency testing in ovarian cancer based on next-generation sequencing].Semantic proximity Read

Structural variants at the <i>BRCA1/2</i> loci are a common source of homologous repair deficiency in high grade serous ovarian carcinomaSemantic proximity Read

Concurrent RB1 loss and<i>BRCA</i>-deficiency predicts enhanced immunological response and long-term survival in tubo-ovarian high-grade serous carcinomaSemantic proximity Read

Homologous recombination inquiry through ovarian malignancy investigations: JGOG3025 StudySemantic proximity Read

Homologous Recombination Inquiry Through Ovarian Malignancy Investigations: The Japanese Gynecologic Oncology Group study JGOG3025Semantic proximity Read

Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancerSemantic proximity Read